ESD Endoscopic Submucosal Dissection
The most advanced technique for treating precancerous lesions and early-stage cancers of the digestive tract
National Cancer Center Tokyo Training
Hospital La Paz • INMEQ Madrid
What is Endoscopic Submucosal Dissection (ESD)?
Endoscopic Submucosal Dissection (ESD) is a minimally invasive endoscopic technique that allows complete resection of precancerous lesions and early-stage cancers of the digestive tract. Unlike other techniques, ESD enables obtaining the lesion in a single block ("en bloc" resection), providing more accurate pathological diagnosis and significantly reducing the risk of recurrence.
As a specialist trained at the National Cancer Center Tokyo in 2013 and being one of the pioneers of ESD in Spain, I have developed exceptional experience in this revolutionary technique that is transforming the treatment of complex digestive lesions.
Clinical Experience
International Training and European Leadership
National Cancer Center Tokyo
Specialized ESD training at one of the world's leading centers in 2013, where the most advanced endoscopic submucosal dissection techniques were developed.
European Board Advisor
Recognized as European Board Advisor of Olympus, the world's leading brand in endoscopy, advising on the development of new technologies and techniques.
International Trainer
Active trainer of endoscopists in Spain and Europe, transmitting the most advanced ESD techniques to the new generation of specialists.
SITE Technique - Saline Immersion
What is the SITE Technique?
The SITE (Saline Immersion Technique) consists of complete immersion of the lesion in saline solution during the ESD procedure. This innovative technique that I routinely use offers multiple advantages over conventional technique.
SITE vs. Conventional Technique Advantages
Microscopic Precision
The SITE technique allows more precise dissection at the microscopic level, ensuring clear margins and minimizing the risk of local recurrence.
Advantages of Endoscopic Submucosal Dissection
Complete resection in a single block (en bloc)
Allows obtaining the complete lesion intact, facilitating precise histopathological analysis and reducing the risk of local recurrence.
More accurate pathological diagnosis
En bloc resection allows complete histological study, accurately determining the degree of invasion and the need for additional treatments.
Avoids major surgeries or organ removal
Allows treating complex lesions without the need for aggressive surgical interventions, preserving the normal function and anatomy of the organ.
Outpatient procedure or brief admission
In most cases it is performed outpatient or with hospitalization of less than 24 hours, minimizing disruption to daily life.
Recovery in a few days
Patients experience rapid and comfortable recovery, being able to resume their usual activities within 24-72 hours, depending on case complexity.
Advanced SITE technique
Use of saline immersion technique that reduces procedure time by 40% and bleeding by 60% compared to conventional techniques.
Patient Testimonials
My patients' trust is my greatest recognition. Learn about their experiences with ESD technique and the results obtained.
Victor's Testimonial
Real experience after endoscopic submucosal dissection for a large polyp performed by Dr. Pedro de María Pallarés. Rapid recovery and excellent results.
"I have been tremendously fortunate to be treated by Dr. Pedro de María. What he did for me is a very well-established operation. I had cancer in the esophageal mucosa, and through the mouth he performed an endoscopic submucosal dissection. I would highlight not only how good a surgeon he is, but his human side, the follow-up he has been providing me constantly. I am alive thanks to his skill, his constant support with the logical complications of a post-operative period, adding to my medical condition. Always attentive, always caring, always resolute. I have no words to express the gratitude I have for him. His vocation is evident from miles away."
Real ESD Clinical Case
Real example of endoscopic submucosal dissection performed at our center. Documented case with complete patient follow-up.
Successful Endoscopic Submucosal Dissection
Documented real case of endoscopic submucosal dissection using SITE technique. The procedure allowed complete en bloc removal of a complex lesion, with clear margins and no complications.
View Complete CaseProcedure Details
Importance of ESD
This case demonstrates the efficacy of ESD for treating complex lesions that previously required major surgery. The technique allows preserving the organ and its function while ensuring complete lesion removal.
Frequently asked questions about ESD
Resolve your doubts about endoscopic submucosal dissection and the SITE technique we use at our center.
In most cases, yes. ESD allows removing lesions with clear margins and reducing the risk of recurrence without the need for conventional surgery. As a minimally invasive technique, it offers oncological results comparable to surgery but with lower morbidity and better quality of life for the patient.
No. ESD is performed under deep sedation or general anesthesia, so the patient does not experience pain during the procedure. The postoperative period is generally comfortable, with minimal discomfort that is effectively controlled with conventional analgesia.
Most patients resume their usual life in 24-72 hours, depending on the type of lesion and area treated. Recovery is significantly faster than conventional surgery, allowing early return to work and social activities.
The SITE (Saline Immersion Technique) that I routinely employ offers superior vision during dissection, reduces collateral damage by 60%, decreases procedure time by 40% and provides cleaner and more precise resection margins, increasing the safety and efficacy of treatment.
As one of the pioneers of ESD in Spain, trained at the National Cancer Center Tokyo in 2013 and European Board Advisor of Olympus, I have developed exceptional experience with en bloc resection rates above 90% and perforation rates of 3%. Additionally, I actively train endoscopists in Spain and Europe in this advanced technique.
ESD is performed at Hospital Universitario La Paz and INMEQ in Madrid. For private consultations at INMEQ, the initial consultation price is 150€. The procedure cost will be evaluated individually according to case complexity. Contact us for a personalized assessment.
Do you have precancerous lesions or early-stage cancer of the digestive tract?
Dr. Pedro de María performs Endoscopic Submucosal Dissection (ESD) with SITE technique at Hospital Universitario La Paz and INMEQ in Madrid. As European Board Advisor of Olympus and pioneer of ESD in Spain, he offers the most advanced experience in this revolutionary technique.
Hospital Universitario La Paz • INMEQ Madrid
Personalized assessment • SITE technique • +90% en bloc resection