Gastric polyps: everything you need to know in 2026

Gastric polyps: everything you need to know in 2026
Published on March 21, 2026

Gastric polyps: everything you need to know in 2026

What they are, why they appear, when they should be removed, and why in most cases they do not mean cancer.

9–11 min read Evidence-based Explained for patients
Gastric polyps explained clearly for patients

Most gastric polyps are benign, but it is important to know exactly which type they are.

TL;DR

What matters most:

  • • Gastric polyps are found in a small percentage of gastroscopies, roughly 0.3–6%.
  • • The most common types are hyperplastic polyps and fundic gland polyps.
  • • Most of them do not become malignant.

What really matters:

  • • Risk depends on the type, size, and whether dysplasia is present.
  • Helicobacter pylori, atrophic gastritis, and PPIs play a major role.
  • • Treatment ranges from simple monitoring to endoscopic removal.

Gastric polyps are small growths that appear on the inner lining of the stomach and, although the name sounds alarming, the most common situation is that they are benign findings discovered during a gastroscopy performed for another reason. What matters is not just seeing “a polyp,” but knowing which kind of polyp it is, whether there is background inflammation, whether Helicobacter pylori is present, whether you take omeprazole or similar medications, and whether the tissue shows any precancerous changes.12

Quick contents

What exactly are gastric polyps?

Think of them as a small bump or tiny lump that sticks out from the stomach lining. Some are very small and smooth; others are larger, multiple, or attached by a stalk. Many people feel absolutely nothing and only find out because they had a gastroscopy for reflux, anaemia, pain, indigestion, or follow-up of another digestive issue.3

Here is the key point: the endoscopic image gives clues, but the biopsy or complete removal is what really tells us what kind of polyp it is. That is why, if you have ever been told “you have a gastric polyp,” the next sensible question is: “right… but what type is it?”45

Types of gastric polyps: they are not all the same

Reassuring message: the word “polyp” does not automatically mean “bad tumour.” In the stomach, most of the polyps we see in daily practice are benign or very low risk.

1) Hyperplastic polyps

These are among the most common and usually appear in a stomach that has been inflamed for a long time. They are especially linked to chronic gastritis, atrophic gastritis, and H. pylori. Very often they are benign, but if they grow larger, are multiple, or the surrounding tissue is abnormal, they deserve closer attention.37

2) Fundic gland polyps

These are very typical in people who have been taking proton pump inhibitors such as omeprazole, esomeprazole, or pantoprazole for a long time. They usually appear in the upper part of the stomach and, when they are sporadic, they carry a very low malignant risk. In plain language: these are usually the least worrying ones.36

3) Gastric adenomas

This is where we need to be more serious, because adenomas have a greater potential to progress toward cancer than other polyps. That does not mean they already are cancer, but it does mean they usually require complete removal and careful follow-up. So when a pathology report says “adenoma” or “dysplasia,” precision and high-quality endoscopy matter.45

4) Other less common lesions

There are also cardiac polyps, inflammatory lesions, type 1 neuroendocrine tumours in the setting of autoimmune gastritis, and polyps linked to hereditary syndromes such as familial adenomatous polyposis. They are less common, but they can change the surveillance plan quite a lot.912

Gastric polyp types: quick comparison

The key is not just “having a polyp,” but knowing which type it is and whether it needs monitoring or treatment.

Hyperplastic polyps

Low risk

Among the most common. They usually appear when the stomach lining has been inflamed for a long time.

Typical cause: chronic gastritis, H. pylori, atrophy.
When to watch more closely: if they are large, multiple, or show dysplasia.
What is usually done: biopsy or removal depending on size and appearance.

Fundic gland polyps

Very low risk

Very typical in people who have been taking omeprazole or similar drugs for a long time.

Typical cause: long-term PPI use.
When to watch more closely: if they are numerous, large, or there is genetic suspicion.
What is usually done: monitor them; remove them if they are larger or change in appearance.

Gastric adenomas

Higher risk

Less common, but these are the ones that deserve the most attention.

Typical cause: atrophy, intestinal metaplasia, altered stomach lining.
When to watch more closely: basically always.
What is usually done: complete resection and close follow-up.

Polyps in autoimmune gastritis

Variable risk

Here, the background stomach environment matters as much as the polyp itself.

Typical cause: autoimmune gastritis, atrophy, hypergastrinemia.
When to watch more closely: if adenomas or neuroendocrine tumours are present.
What is usually done: scheduled surveillance and individualised treatment.
Quick takeaway: most gastric polyps do not become malignant. The most reassuring ones are usually fundic gland polyps, while adenomas are the ones that need the closest attention.

How common are they and who gets them?

Gastric polyps are not extremely rare, but they are not found in every gastroscopy either. Depending on the published series, they appear in roughly 0.3 to 6% of upper digestive endoscopies, with differences depending on the country, the prevalence of H. pylori, the use of PPIs, and the type of patients studied.128

In a large series of more than 18,000 gastroscopies, the prevalence was 0.46%, and hyperplastic polyps were the most frequent, followed by fundic gland polyps and adenomas. They are also more often seen after the age of 50–60, and several studies show a slight female predominance, although this can vary depending on the type of polyp.18

Risk factors and why they appear

This is the most useful part: gastric polyps do not just appear “out of nowhere.” Very often they are the footprint of something already going on inside the stomach. The classic example is Helicobacter pylori, which promotes chronic gastritis, atrophy, and an environment where hyperplastic polyps and adenomas are more likely.34

Another major factor is PPI use. Taking these drugs for a long time is associated with more fundic gland polyps, especially in stomachs without H. pylori. That does not mean omeprazole is the villain of the story. It means that if someone has many fundic polyps or large ones, it is sensible to review whether the treatment is still needed and at what dose.36

Autoimmune or atrophic gastritis also matters. In that setting, long-standing inflammation, hypergastrinemia, and a higher probability of inflammatory polyps, adenomas, or type 1 neuroendocrine tumours can all come into play. In other words: when the “soil” of the stomach is altered, surveillance needs to be different.39

And yes, other ingredients also matter: age, lifestyle, gastroesophageal reflux, bile reflux, and hereditary syndromes. Some studies have linked greater risk to very hot food, low fruit intake, irregular eating habits, and specific genetic backgrounds.101112

Can they turn into cancer?

Short answer: most of them do not. But some do carry risk, which is why the topic should never be dismissed with a simple “let’s just wait and see.”

Sporadic fundic gland polyps usually carry a very low malignant risk. Hyperplastic polyps carry a low but real risk, and that risk increases if they are larger than 1–2 cm, multiple, pedunculated, or if the surrounding mucosa shows metaplasia or dysplasia. In some series, neoplastic transformation is around 5%, although not every study finds exactly the same number.67

In a large study of 4,010 hyperplastic polyps, neoplasia was still uncommon, but it was seen more often in people older than 65, in men, in multiple or larger polyps, and when the background stomach showed atrophic or autoimmune gastritis. That confirms a very practical idea: risk depends on the context, not just on the bump itself.8

Treatment and when they should be removed

Treatment is not the same for everyone. In general, the first step is to describe the polyp properly during endoscopy and obtain histology. Many experts recommend complete resection when dealing with epithelial polyps measuring 5–10 mm or more, when dysplasia is present, when the appearance is suspicious for a precancerous lesion, or when size starts to become a concern.45

In real life, the plan usually includes:

  • • Biopsy or resection to know exactly what type of polyp it is.
  • • Eradication of H. pylori if present.
  • • Reviewing whether PPIs are still necessary if fundic polyps are numerous or large.
  • • Planned surveillance if the type of polyp or the “background stomach” justifies it.

The good news is that many gastric polyps can be treated without open surgery. Advanced endoscopy makes it possible to assess the lesion in detail and, if needed, remove it in a minimally invasive way. Smaller or intermediate lesions are often treated with endoscopic mucosal resection (EMR), while larger, flatter, or more complex lesions may require endoscopic submucosal dissection (ESD).45

I Want to Book an Appointment

If you have been told you have a gastric polyp and want to know whether it should be removed, monitored, or simply better understood, we can sort it out clearly with you.

Follow-up: what to expect afterwards

Follow-up depends heavily on the pathology report. If the polyp was low risk, small, and showed no worrying features, sometimes it is enough to address the underlying cause and arrange sensible surveillance. If it was an adenoma, if dysplasia was present, or if there is autoimmune gastritis, atrophic gastritis, or a hereditary syndrome, follow-up needs to be more structured.4912

The point is not to live in fear, but to live with a plan. Good follow-up is what prevents nasty surprises and allows action at the right moment if a new lesion appears or if the stomach lining changes over time. Good medicine is not about scaring people. It is about staying one step ahead.

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A personal note

When someone hears “we found a polyp,” imagination usually moves faster than reality. My job is not only to perform endoscopy. It is also to translate complexity into plain language, so you understand what is happening and what needs to be done without unnecessary drama.

Operating room selfie giving a thumbs up

Main studies and guidelines

  1. Yacoub H, Bibani N, Sabbah M, et al. Gastric polyps: a 10-year analysis of 18,496 upper endoscopies. BMC Gastroenterology. Full text
  2. Sonnenberg A, Genta RM. Prevalence of benign gastric polyps in a large pathology database. Digestive and Liver Disease. PubMed
  3. Waldum H, Fossmark R. Gastritis, Gastric Polyps and Gastric Cancer. International Journal of Molecular Sciences. Article
  4. Shaib Y, Rugge M, Graham DY, Genta RM. Management of Gastric Polyps: An Endoscopy-Based Approach. Clinical Gastroenterology and Hepatology. Full text
  5. Goddard AF, Badreldin R, Pritchard DM, Walker MM, Warren B. The management of gastric polyps. Gut. PubMed
  6. Carmack SW, Genta RM, Schuler CM, Saboorian MH. The current spectrum of gastric polyps: a 1-year national study of over 120,000 patients. American Journal of Gastroenterology. PubMed
  7. Markowski AR, Markowska A, Guzinska-Ustymowicz K. Pathophysiological and clinical aspects of gastric hyperplastic polyps. World Journal of Gastroenterology. DOI
  8. Zhang DX, Niu Z, Wang Y, et al. Endoscopic and pathological features of neoplastic transformation of gastric hyperplastic polyps: Retrospective study of 4010 cases. World Journal of Gastrointestinal Oncology. Full text
  9. Massironi S, Gallo C, Lahner E, et al. Occurrence and characteristics of endoscopic gastric polyps in patients with autoimmune gastritis (AGAPE study). PubMed
  10. Zeng S, Liang Y, Wu X, et al. Gastroesophageal reflux is associated with an increased risk of gastric cardiac polyps. PubMed
  11. Cao W, Hou G, Zhang X, San H, Zheng J. Potential risk factors related to the development of gastric polyps. DOI
  12. Christenson R, Sood S, Vierkant R, et al. Gastric polyposis and risk of gastric cancer in patients with familial adenomatous polyposis. DOI

FAQ: quick questions about gastric polyps

Are gastric polyps cancer?

No. Most are benign and never become malignant. Still, the exact type matters because not every polyp carries the same risk.

Do they always need to be removed?

Not always. It depends on the size, endoscopic appearance, histology, and whether dysplasia or a higher-risk context is present.

Can omeprazole influence them?

Yes. Long-term PPI use is associated mainly with fundic gland polyps. These are usually very low risk, but treatment should be reviewed if they are numerous or large.

Does Helicobacter pylori matter?

Yes. It can promote chronic gastritis, atrophy, and some hyperplastic polyps or adenomas. If it is present, eradication is usually the right next step.

What treatment is usually done?

Sometimes biopsy and surveillance are enough. Other times they need to be removed endoscopically, while also treating H. pylori or adjusting medications such as PPIs.

Dr. Pedro de María Pallarés

Dr. Pedro de María Pallarés

Digestive Disease Specialist • Advanced Endoscopy Expert

La Paz University Hospital • INMEQ

🏆 TopDoctors Awards 2024 • Member of SEPD, SEED, ESGE

© 2026. This content is for information only and does not replace personalised medical advice.

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