Endoscopic Mucosectomy in Madrid - Dr. Pedro de María Pallarés | Advanced Endoscopy

Endoscopic Mucosectomy in Madrid

Advanced endoscopy specialist with underwater technique. Minimally invasive treatment of polyps and premalignant lesions of the digestive tract.

European Advisor
Olympus
TopDoctors
Award
Hospital
La Paz
Dr. Pedro de María Pallarés
Advanced Endoscopist - INMEQ | Hospital Universitario La Paz
Endoscopic mucosectomy Dr. Pedro de María Madrid

What is an endoscopic mucosectomy?

As a specialist in advanced endoscopy, one of the techniques I perform most frequently for treating premalignant lesions of the digestive tract is endoscopic mucosectomy or EMR (Endoscopic Mucosal Resection). This minimally invasive technique allows the removal of superficial lesions from the digestive tract without the need for surgery.

Mucosectomy is a therapeutic endoscopic technique that involves the controlled resection of the mucosal layer of the digestive tract—that is, the internal lining where most premalignant and early malignant tumors originate. It is especially useful for flat polyps, adenomas, and dysplastic lesions located in the colon, rectum, esophagus, or stomach.

Why do I perform the underwater technique?

Specialized technique with superior advantages

Although there are several technical variants of mucosectomy, in my practice I preferentially use the underwater technique. This involves filling the intestinal segment with water, avoiding the insufflation of air or CO₂, and facilitating resection without the need for prior submucosal injection.

Key advantages of the underwater technique:

Greater safety

By avoiding air, the intestinal wall is less distended, reducing the risk of perforation.

Better resection rates

By floating the mucosa, complete resection of the lesion in one piece is facilitated.

Clearer visualization

The liquid medium improves visibility of margins and vessels, allowing more precise resection.

More efficient procedures

Shorter procedure times in many cases.

Validated technique: This technique was initially described by Binmoeller in 2012, and since then has demonstrated excellent results in safety and efficacy, especially in right colon and distal rectum lesions.

Common indications in my practice

Flat adenomas of the colon or rectum
Polyps with suspected dysplasia
LST lesions (laterally spreading tumors)
Outpatient procedures

How is underwater mucosectomy performed?

1

The colonoscope is introduced to the area of the lesion.

2

Instead of insufflating air, the colon lumen is filled with water.

3

The lesion unfolds and naturally separates from the muscularis propria without the need for injection.

4

A resection snare is used to cut the lesion en bloc or in fragments (piecemeal), depending on size and location.

5

If necessary, hemostatic clips are placed to close the mucosal defect and prevent bleeding.

Safety and recovery

Outpatient

Outpatient procedure in most cases

Quick recovery

Normal activity in 24-48 hours

Low morbidity

Complications less than 1%

Complications are infrequent and usually mild (self-limited bleeding or mild abdominal distention). In experienced hands, the rate of major complications such as perforation is less than 1%.

My experience in underwater mucosectomy

Since I introduced this technique into my practice, I have been able to perform hundreds of safe and effective resections in patients with lesions that, in another context, might have required surgery.

Reference centers:

  • Hospital San Rafael (Madrid)
  • Hospital Fuensanta (Madrid)
  • Hospital Universitario La Paz

Recognition:

  • European Advisor Olympus
  • TopDoctors Award
  • IMEQ Co-founder

When is this technique indicated?

If you have been diagnosed with a flat polyp, suspicious lesion in the colon or duodenum, underwater mucosectomy can be a safe and effective alternative to traditional surgery.

I always perform an individualized assessment, supported by advanced imaging techniques (NBI, digital chromoendoscopy) to determine the best therapeutic strategy in each case.

Dr. Pedro de María Pallarés

Digestive System and Advanced Endoscopy Specialist

Hospital Universitario La Paz – IMEQ Co-founder

Frequently Asked Questions

Is underwater mucosectomy painful?

No, mucosectomy is performed under conscious sedation, so the patient does not feel pain during the procedure. It is common to experience mild abdominal discomfort post-procedure that resolves within a few hours.

How long does the procedure take?

Duration varies according to the size and location of the lesion, but generally ranges between 30 and 90 minutes. The underwater technique allows for more efficient procedures in many cases.

Do I need hospitalization after the procedure?

In most cases, it is an outpatient procedure. You can go home the same day after a brief observation period of 2-4 hours to ensure there are no complications.

What are the risks of underwater mucosectomy?

Risks are minimal. The most frequent complications are mild bleeding (usually self-limited) and temporary abdominal distention. The risk of perforation is less than 1% with this technique.

When can I return to my normal activity?

Most patients can resume their normal activities within 24-48 hours. It is recommended to avoid intense efforts and heavy lifting during the first week post-procedure.

Is follow-up necessary after mucosectomy?

Yes, it is essential to perform endoscopic follow-up to verify complete healing and rule out recurrence. The first follow-up is usually performed at 3-6 months, depending on the specific case.

Dr. Pedro de María Pallarés

Specialist in Endoscopic Mucosectomy and Advanced Endoscopy in Madrid

Hospital San Rafael Hospital Fuensanta Hospital La Paz